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MiR-21 in Extracellular Vesicles Leads to Neurotoxicity via TLR7 Signaling in SIV Neurological Disease
Recent studies have found that extracellular vesicles (EVs) play an important role in normal and disease processes. In the present study, we isolated and characterized EVs from the brains of rhesus macaques, both with and without simian immunodeficiency virus (SIV) induced central nervous system (CN...
Autores principales: | Yelamanchili, Sowmya V., Lamberty, Benjamin G., Rennard, Deborah A., Morsey, Brenda M., Hochfelder, Colleen G., Meays, Brittney M., Levy, Efrat, Fox, Howard S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496044/ https://www.ncbi.nlm.nih.gov/pubmed/26154133 http://dx.doi.org/10.1371/journal.ppat.1005032 |
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