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The Effects of the Recombinant CCR5 T4 Lysozyme Fusion Protein on HIV-1 Infection

BACKGROUND: Insertion of T4 lysozyme (T4L) into the GPCR successfully enhanced GPCR protein stability and solubilization. However, the biological functions of the recombinant GPCR protein have not been analyzed. METHODS: We engineered the CCR5-T4L mutant and expressed and purified the soluble recomb...

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Detalles Bibliográficos
Autores principales: Jin, Qingwen, Chen, Hong, Wang, Xingxia, Zhao, Liandong, Xu, Qingchen, Wang, Huijuan, Li, Guanyu, Yang, Xiaofan, Ma, Hongming, Wu, Haoquan, Ji, Xiaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496087/
https://www.ncbi.nlm.nih.gov/pubmed/26154172
http://dx.doi.org/10.1371/journal.pone.0131894