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The Effects of the Recombinant CCR5 T4 Lysozyme Fusion Protein on HIV-1 Infection
BACKGROUND: Insertion of T4 lysozyme (T4L) into the GPCR successfully enhanced GPCR protein stability and solubilization. However, the biological functions of the recombinant GPCR protein have not been analyzed. METHODS: We engineered the CCR5-T4L mutant and expressed and purified the soluble recomb...
Autores principales: | Jin, Qingwen, Chen, Hong, Wang, Xingxia, Zhao, Liandong, Xu, Qingchen, Wang, Huijuan, Li, Guanyu, Yang, Xiaofan, Ma, Hongming, Wu, Haoquan, Ji, Xiaohui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496087/ https://www.ncbi.nlm.nih.gov/pubmed/26154172 http://dx.doi.org/10.1371/journal.pone.0131894 |
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