Screening for FtsZ Dimerization Inhibitors Using Fluorescence Cross-Correlation Spectroscopy and Surface Resonance Plasmon Analysis

FtsZ is an attractive target for antibiotic research because it is an essential bacterial cell division protein that polymerizes in a GTP-dependent manner. To find the seed chemical structure, we established a high-throughput, quantitative screening method combining fluorescence cross-correlation sp...

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Detalles Bibliográficos
Autores principales: Mikuni, Shintaro, Kodama, Kota, Sasaki, Akira, Kohira, Naoki, Maki, Hideki, Munetomo, Masaharu, Maenaka, Katsumi, Kinjo, Masataka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496089/
https://www.ncbi.nlm.nih.gov/pubmed/26154290
http://dx.doi.org/10.1371/journal.pone.0130933

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496089/
https://www.ncbi.nlm.nih.gov/pubmed/26154290
http://dx.doi.org/10.1371/journal.pone.0130933

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