Geraniol Suppresses Angiogenesis by Downregulating Vascular Endothelial Growth Factor (VEGF)/VEGFR-2 Signaling

Geraniol exerts several direct pharmacological effects on tumor cells and, thus, has been suggested as a promising anti-cancer compound. Because vascularization is a major precondition for tumor growth, we analyzed in this study the anti-angiogenic action of geraniol. In vitro, geraniol reduced the...

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Detalles Bibliográficos
Autores principales: Wittig, Christine, Scheuer, Claudia, Parakenings, Julia, Menger, Michael D., Laschke, Matthias W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496091/
https://www.ncbi.nlm.nih.gov/pubmed/26154255
http://dx.doi.org/10.1371/journal.pone.0131946

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496091/
https://www.ncbi.nlm.nih.gov/pubmed/26154255
http://dx.doi.org/10.1371/journal.pone.0131946

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