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Geraniol Suppresses Angiogenesis by Downregulating Vascular Endothelial Growth Factor (VEGF)/VEGFR-2 Signaling
Geraniol exerts several direct pharmacological effects on tumor cells and, thus, has been suggested as a promising anti-cancer compound. Because vascularization is a major precondition for tumor growth, we analyzed in this study the anti-angiogenic action of geraniol. In vitro, geraniol reduced the...
Autores principales: | Wittig, Christine, Scheuer, Claudia, Parakenings, Julia, Menger, Michael D., Laschke, Matthias W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496091/ https://www.ncbi.nlm.nih.gov/pubmed/26154255 http://dx.doi.org/10.1371/journal.pone.0131946 |
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