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Mouse models with human immunity and their application in biomedical research

Biomedical research in human beings is largely restricted to in vitro studies that lack complexity of a living organism. To overcome this limitation, humanized mouse models are developed based on immunodeficient characteristics of severe combined immunodeficiency (SCID) or recombination activating g...

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Detalles Bibliográficos
Autores principales: Zhang, Baojun, Duan, Ziyuan, Zhao, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496103/
https://www.ncbi.nlm.nih.gov/pubmed/18419795
http://dx.doi.org/10.1111/j.1582-4934.2008.00347.x