Cargando…
Mitochondrial accumulation of APP and Aβ: significance for Alzheimer disease pathogenesis
Accumulating evidence suggest that alterations in energy metabolism are among the earliest events that occur in the Alzheimer disease (AD) affected brain. Energy consumption is drastically decreased in the AD-affected regions of cerebral cortex and hippocampus pointing towards compromised mitochondr...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496119/ https://www.ncbi.nlm.nih.gov/pubmed/19725915 http://dx.doi.org/10.1111/j.1582-4934.2009.00892.x |