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Mitochondrial accumulation of APP and Aβ: significance for Alzheimer disease pathogenesis

Accumulating evidence suggest that alterations in energy metabolism are among the earliest events that occur in the Alzheimer disease (AD) affected brain. Energy consumption is drastically decreased in the AD-affected regions of cerebral cortex and hippocampus pointing towards compromised mitochondr...

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Detalles Bibliográficos
Autores principales: Pavlov, Pavel F, Petersen, Camilla Hansson, Glaser, Elzbieta, Ankarcrona, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496119/
https://www.ncbi.nlm.nih.gov/pubmed/19725915
http://dx.doi.org/10.1111/j.1582-4934.2009.00892.x