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Serum withdrawal up-regulates human SIRT1 gene expression in a p53-dependent manner
SIRT1, a nicotinamide adenine dinucleotide (NAD(+))-dependent histone/protein deacetylase, has been extensively studied recently for its critical role in the regulation of physiology, calorie restriction and aging. Studies on laboratory mice showed that expression of SIRT1 can be induced by starvati...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley & Sons, Ltd
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496124/ https://www.ncbi.nlm.nih.gov/pubmed/19267881 http://dx.doi.org/10.1111/j.1582-4934.2008.00468.x |