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Lack of inhibitory effects of the anti-fibrotic drug imatinib on endothelial cell functions in vitro and in vivo

Systemic sclerosis (SSc) is a systemic autoimmune disease that is characterized by microangiopathy with progressive loss of capillaries and tissue fibrosis. Imatinib exerts potent anti-fibrotic effects and is currently evaluated in clinical trials. The aim of the present study was to exclude that th...

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Detalles Bibliográficos
Autores principales: Venalis, Paulius, Maurer, Britta, Akhmetshina, Alfiya, Busch, Nicole, Dees, Clara, Stürzl, Michael, Zwerina, Jochen, Jüngel, Astrid, Gay, Steffen, Schett, Georg, Distler, Oliver, Distler, Jörg HW
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496125/
https://www.ncbi.nlm.nih.gov/pubmed/18774958
http://dx.doi.org/10.1111/j.1582-4934.2008.00492.x