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Identification of a novel pro-apopotic function of NF-κB in the DNA damage response

NF-κB is activated by DNA-damaging anticancer drugs as part of the cellular stress response. However, the consequences of drug-induced NF-κB activation are still only partly understood. To investigate the impact of NF-κB on the cell’s response to DNA damage, we engineered glioblastoma cells that sta...

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Detalles Bibliográficos
Autores principales: Karl, Sabine, Pritschow, Yvonne, Volcic, Meta, Häcker, Sabine, Baumann, Bernd, Wiesmüller, Lisa, Debatin, Klaus-Michael, Fulda, Simone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496130/
https://www.ncbi.nlm.nih.gov/pubmed/19725919
http://dx.doi.org/10.1111/j.1582-4934.2009.00888.x