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Healthy human salivary glands contain a DHEA-sulphate processing intracrine machinery, which is deranged in primary Sjögren’s syndrome

Sjögren’s syndrome (SS) patients have low salivary dehydroepiandrosterone (DHEA) and androgen biomarker levels, but high salivary oestrogen levels. The hypothesis was that the healthy glands contain DHEA-sulphate processing intracrine machinery; the local androgen/oestrogen imbalance suggests that t...

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Detalles Bibliográficos
Autores principales: Spaan, Michelle, Porola, Pauliina, Laine, Mikael, Rozman, Blaz, Azuma, Masayuki, Konttinen, Yrjö T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496140/
https://www.ncbi.nlm.nih.gov/pubmed/19298523
http://dx.doi.org/10.1111/j.1582-4934.2009.00727.x