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Immunohistochemical detection of polyductin and co-localization with liver progenitor cell markers during normal and abnormal development of the intrahepatic biliary system and in adult hepatobiliary carcinomas

The longest open reading frame of PKHD1 (polycystic kidney and hepatic disease 1), the autosomal recessive polycystic kidney disease (ARPKD) gene, encodes a single-pass, integral membrane protein named polyductin or fibrocystin. A fusion protein comprising its intracellular C-terminus, FP2, was prev...

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Detalles Bibliográficos
Autores principales: Dorn, Livia, Menezes, Luís F, Mikuz, Gregor, Otto, Herwart F, Onuchic, Luiz F, Sergi, Consolato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496142/
https://www.ncbi.nlm.nih.gov/pubmed/19292732
http://dx.doi.org/10.1111/j.1582-4934.2008.00519.x