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Immunohistochemical detection of polyductin and co-localization with liver progenitor cell markers during normal and abnormal development of the intrahepatic biliary system and in adult hepatobiliary carcinomas
The longest open reading frame of PKHD1 (polycystic kidney and hepatic disease 1), the autosomal recessive polycystic kidney disease (ARPKD) gene, encodes a single-pass, integral membrane protein named polyductin or fibrocystin. A fusion protein comprising its intracellular C-terminus, FP2, was prev...
Autores principales: | Dorn, Livia, Menezes, Luís F, Mikuz, Gregor, Otto, Herwart F, Onuchic, Luiz F, Sergi, Consolato |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496142/ https://www.ncbi.nlm.nih.gov/pubmed/19292732 http://dx.doi.org/10.1111/j.1582-4934.2008.00519.x |
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