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RAD001 (everolimus) inhibits tumour growth in xenograft models of human hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is the fifth most common malignancy worldwide and highly resistant to available chemotherapies. Mammalian target of rapamycin (mTOR) functions to regulate protein translation, angiogenesis and cell cycle progression in many cancers including HCC. In the present study,...

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Detalles Bibliográficos
Autores principales: Huynh, Hung, Pierce Chow, KH, Soo, Khee Chee, Toh, Han Chong, Choo, Su Pin, Foo, Kian Fong, Poon, Donald, Ngo, Van Chanh, Tran, Evelyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496150/
https://www.ncbi.nlm.nih.gov/pubmed/18466352
http://dx.doi.org/10.1111/j.1582-4934.2008.00364.x