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RAD001 (everolimus) inhibits tumour growth in xenograft models of human hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is the fifth most common malignancy worldwide and highly resistant to available chemotherapies. Mammalian target of rapamycin (mTOR) functions to regulate protein translation, angiogenesis and cell cycle progression in many cancers including HCC. In the present study,...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496150/ https://www.ncbi.nlm.nih.gov/pubmed/18466352 http://dx.doi.org/10.1111/j.1582-4934.2008.00364.x |