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A mutation in the NADH-dehydrogenase subunit 2 suppresses fibroblast aging

Mutations of mitochondrial (mt)DNA cause a variety of human diseases and are implicated in premature aging syndromes. Here we investigated a single nucleotide exchange (leucine to methionine) at position nt4738 in the mitochondrial NADH dehydrogenase subunit 2 (Nd2) gene of the respiratory chain. Pr...

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Detalles Bibliográficos
Autores principales: Schauer, Marianne, Kottek, Tina, Schönherr, Madeleine, Bhattacharya, Animesh, Ibrahim, Saleh M, Hirose, Misa, Köhling, Rüdiger, Fuellen, Georg, Schmitz, Ulf, Kunz, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496166/
https://www.ncbi.nlm.nih.gov/pubmed/25839158