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A mutation in the NADH-dehydrogenase subunit 2 suppresses fibroblast aging

Mutations of mitochondrial (mt)DNA cause a variety of human diseases and are implicated in premature aging syndromes. Here we investigated a single nucleotide exchange (leucine to methionine) at position nt4738 in the mitochondrial NADH dehydrogenase subunit 2 (Nd2) gene of the respiratory chain. Pr...

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Detalles Bibliográficos
Autores principales:	Schauer, Marianne, Kottek, Tina, Schönherr, Madeleine, Bhattacharya, Animesh, Ibrahim, Saleh M, Hirose, Misa, Köhling, Rüdiger, Fuellen, Georg, Schmitz, Ulf, Kunz, Manfred
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Gerotarget (Focus on Aging): Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496166/ https://www.ncbi.nlm.nih.gov/pubmed/25839158

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