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Dual effects of collagenase-3 on melanoma: metastasis promotion and disruption of vasculogenic mimicry

Vasculogenic mimicry (VM) is a functional microcirculation formed by tumor cells. Matrix metalloproteinases (MMPs), especially MMP-2 and MMP-9, promote VM formation. Another specific MMP, collagenase-3 (MMP-13), has broad substrate specificity and potentially affects tumor metastasis and invasion. H...

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Detalles Bibliográficos
Autores principales: Zhao, Xiulan, Sun, Baocun, Li, Yanlei, Liu, Yanrong, Zhang, Danfang, Wang, Xudong, Gu, Qiang, Zhao, Jianmin, Dong, Xueyi, Liu, Zhiyong, Che, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496190/
https://www.ncbi.nlm.nih.gov/pubmed/25749207