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IL-32α suppresses colorectal cancer development via TNFR1-mediated death signaling

Inflammation is associated with cancer-prone microenvironment, leading to cancer. IL-32 is expressed in chronic inflammation-linked human cancers. To investigate IL-32α in inflammation-linked colorectal carcinogenesis, we generated a strain of mice, expressing IL-32 (IL-32α-Tg). In IL-32α-Tg mice, a...

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Detalles Bibliográficos
Autores principales: Yun, Hyung-Mun, Park, Kyung-Ran, Kim, Eun-Cheol, Han, Sang Bae, Yoon, Do Young, Hong, Jin Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496202/
https://www.ncbi.nlm.nih.gov/pubmed/25909160