ANO1/TMEM16A interacts with EGFR and correlates with sensitivity to EGFR-targeting therapy in head and neck cancer

The epidermal growth factor receptor (EGFR) contributes to the pathogenesis of head&neck squamous cell carcinoma (HNSCC). However, only a subset of HNSCC patients benefit from anti-EGFR targeted therapy. By performing an unbiased proteomics screen, we found that the calcium-activated chloride ch...

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Detalles Bibliográficos
Autores principales: Bill, Anke, Gutierrez, Abraham, Kulkarni, Sucheta, Kemp, Carolyn, Bonenfant, Debora, Voshol, Hans, Duvvuri, Umamaheswar, Gaither, L. Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496210/
https://www.ncbi.nlm.nih.gov/pubmed/25823819

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496210/
https://www.ncbi.nlm.nih.gov/pubmed/25823819

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