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ANO1/TMEM16A interacts with EGFR and correlates with sensitivity to EGFR-targeting therapy in head and neck cancer
The epidermal growth factor receptor (EGFR) contributes to the pathogenesis of head&neck squamous cell carcinoma (HNSCC). However, only a subset of HNSCC patients benefit from anti-EGFR targeted therapy. By performing an unbiased proteomics screen, we found that the calcium-activated chloride ch...
Autores principales: | Bill, Anke, Gutierrez, Abraham, Kulkarni, Sucheta, Kemp, Carolyn, Bonenfant, Debora, Voshol, Hans, Duvvuri, Umamaheswar, Gaither, L. Alex |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496210/ https://www.ncbi.nlm.nih.gov/pubmed/25823819 |
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