Cargando…
Dynamic Binding Mode of a Synaptotagmin-1-SNARE Complex in Solution
Rapid neurotransmitter release depends on the Ca(2+)-sensor Synaptotagmin-1 and the SNARE complex formed by synaptobrevin, syntaxin-1 and SNAP-25. How Synaptotagmin-1 triggers release remains unclear, in part because elucidating high-resolution structures of Synaptotagmin-1-SNARE complexes has been...
Autores principales: | Brewer, Kyle D., Bacaj, Taulant, Cavalli, Andrea, Camilloni, Carlo, Swarbrick, James D., Liu, Jin, Zhou, Amy, Zhou, Peng, Barlow, Nicholas, Xu, Junjie, Seven, Alpay B., Prinslow, Eric A., Voleti, Rashmi, Häussinger, Daniel, Bonvin, Alexandre M.J.J., Tomchick, Diana R., Vendruscolo, Michele, Graham, Bim, Südhof, Thomas C., Rizo, Josep |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496268/ https://www.ncbi.nlm.nih.gov/pubmed/26030874 http://dx.doi.org/10.1038/nsmb.3035 |
Ejemplares similares
-
Architecture of the Synaptotagmin-SNARE Machinery for Neuronal Exocytosis
por: Zhou, Qiangjun, et al.
Publicado: (2015) -
Ca(2+)-dependent release of synaptotagmin-1 from the SNARE complex on phosphatidylinositol 4,5-bisphosphate-containing membranes
por: Voleti, Rashmi, et al.
Publicado: (2020) -
Extended Synaptotagmin (ESyt) Triple Knock-Out Mice Are Viable and Fertile without Obvious Endoplasmic Reticulum Dysfunction
por: Sclip, Alessandra, et al.
Publicado: (2016) -
Synaptotagmin-1 and -7 Are Redundantly Essential for Maintaining the Capacity of the Readily-Releasable Pool of Synaptic Vesicles
por: Bacaj, Taulant, et al.
Publicado: (2015) -
Postsynaptic Synaptotagmins Mediate AMPA Receptor Exocytosis During LTP
por: Wu, Dick, et al.
Publicado: (2017)