Dynamic Binding Mode of a Synaptotagmin-1-SNARE Complex in Solution

Rapid neurotransmitter release depends on the Ca(2+)-sensor Synaptotagmin-1 and the SNARE complex formed by synaptobrevin, syntaxin-1 and SNAP-25. How Synaptotagmin-1 triggers release remains unclear, in part because elucidating high-resolution structures of Synaptotagmin-1-SNARE complexes has been...

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Detalles Bibliográficos
Autores principales: Brewer, Kyle D., Bacaj, Taulant, Cavalli, Andrea, Camilloni, Carlo, Swarbrick, James D., Liu, Jin, Zhou, Amy, Zhou, Peng, Barlow, Nicholas, Xu, Junjie, Seven, Alpay B., Prinslow, Eric A., Voleti, Rashmi, Häussinger, Daniel, Bonvin, Alexandre M.J.J., Tomchick, Diana R., Vendruscolo, Michele, Graham, Bim, Südhof, Thomas C., Rizo, Josep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496268/
https://www.ncbi.nlm.nih.gov/pubmed/26030874
http://dx.doi.org/10.1038/nsmb.3035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496268/
https://www.ncbi.nlm.nih.gov/pubmed/26030874
http://dx.doi.org/10.1038/nsmb.3035

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