Postsynaptic Synaptotagmins Mediate AMPA Receptor Exocytosis During LTP

Strengthening of synaptic connections by NMDA-receptor-dependent long-term potentiation (LTP) shapes neural circuits and mediates learning and memory. During NMDA-receptor-dependent LTP induction, Ca(2+)-influx stimulates recruitment of synaptic AMPA-receptors, thereby strengthening synapses. How Ca...

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Detalles Bibliográficos
Autores principales: Wu, Dick, Bacaj, Taulant, Morishita, Wade, Goswami, Debanjan, Arendt, Kristin L., Xu, Wei, Chen, Lu, Malenka, Robert C., Südhof, Thomas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734942/
https://www.ncbi.nlm.nih.gov/pubmed/28355182
http://dx.doi.org/10.1038/nature21720

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734942/
https://www.ncbi.nlm.nih.gov/pubmed/28355182
http://dx.doi.org/10.1038/nature21720

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