Extended Synaptotagmin (ESyt) Triple Knock-Out Mice Are Viable and Fertile without Obvious Endoplasmic Reticulum Dysfunction

Extended synaptotagmins (ESyts) are endoplasmic reticulum (ER) proteins composed of an N-terminal transmembrane region, a central SMP-domain, and five (ESyt1) or three C-terminal cytoplasmic C2-domains (ESyt2 and ESyt3). ESyts bind phospholipids in a Ca(2+)-dependent manner via their C2-domains, are...

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Detalles Bibliográficos
Autores principales: Sclip, Alessandra, Bacaj, Taulant, Giam, Louise R., Südhof, Thomas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922586/
https://www.ncbi.nlm.nih.gov/pubmed/27348751
http://dx.doi.org/10.1371/journal.pone.0158295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922586/
https://www.ncbi.nlm.nih.gov/pubmed/27348751
http://dx.doi.org/10.1371/journal.pone.0158295

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