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NF2 blocks Snail-mediated p53 suppression in mesothelioma

Although asbestos causes malignant pleural mesothelioma (MPM), rising from lung mesothelium, the molecular mechanism has not been suggested until now. Extremely low mutation rate in classical tumor suppressor genes (such as p53 and pRb) and oncogenes (including Ras or myc) indicates that there would...

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Detalles Bibliográficos
Autores principales: Cho, Jung-Hyun, Lee, Su-Jin, Oh, Ah-Young, Yoon, Min-Ho, Woo, Tae-Geun, Park, Bum-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496341/
https://www.ncbi.nlm.nih.gov/pubmed/25823924