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Yes-mediated phosphorylation of focal adhesion kinase at tyrosine 861 increases metastatic potential of prostate cancer cells

To study the role of FAK signaling complexes in promoting metastatic properties of prostate cancer (PCa) cells, we selected stable, highly migratory variants, termed PC3 Mig-3 and DU145 Mig-3, from two well-characterized PCa cell lines, PC3 and DU145. These variants were not only increased migration...

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Detalles Bibliográficos
Autores principales: Chatterji, Tanushree, Varkaris, Andreas S., Parikh, Nila U., Song, Jian H., Cheng, Chien-Jui, Schweppe, Rebecca E., Alexander, Stephanie, Davis, John W., Troncoso, Patricia, Friedl, Peter, Kuang, Jian, Lin, Sue-Hwa, Gallick, Gary E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496348/
https://www.ncbi.nlm.nih.gov/pubmed/25868388