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Oncogenic extracellular HSP70 disrupts the gap-junctional coupling between capillary cells

High levels of circulating heat shock protein 70 (HSP70) are detected in many cancers. In order to explore the effects of extracellular HSP70 on human microvascular endothelial cells (HMEC), we initially used gap-FRAP technique. Extracellular human HSP70 (rhHSP70), but not rhHSP27, blocks the gap-ju...

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Detalles Bibliográficos
Autores principales: Thuringer, Dominique, Berthenet, Kevin, Cronier, Laurent, Jego, Gaetan, Solary, Eric, Garrido, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496354/
https://www.ncbi.nlm.nih.gov/pubmed/25868858