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EGCG-mediated autophagy flux has a neuroprotection effect via a class III histone deacetylase in primary neuron cells

Prion diseases caused by aggregated misfolded prion protein (PrP) are transmissible neurodegenerative disorders that occur in both humans and animals. Epigallocatechin-3-gallate (EGCG) has preventive effects on prion disease; however, the mechanisms related to preventing prion diseases are unclear....

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Detalles Bibliográficos
Autores principales: Lee, Ju-Hee, Moon, Ji-Hong, Kim, Sung-Wook, Jeong, Jae-Kyo, Nazim, Uddin MD, Lee, You-Jin, Seol, Jae-Won, Park, Sang-Youel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496391/
https://www.ncbi.nlm.nih.gov/pubmed/25991666