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Delphinidin sensitizes prostate cancer cells to TRAIL-induced apoptosis, by inducing DR5 and causing caspase-mediated HDAC3 cleavage

TRAIL can induce apoptosis in some cancer cells and is an immune effector in the surveillance and elimination of developing tumors. Yes, some cancers are resistant to TRAIL. Delphinidin, a polyphenolic compound contained in brightly colored fruits and vegetables, has anti-inflammatory, anti-oxidant,...

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Detalles Bibliográficos
Autores principales: Ko, Hyeonseok, Jeong, Mi-Hyeon, Jeon, Hyelin, Sung, Gi-Jun, So, Youngsin, Kim, InKi, Son, JaeKyoung, Lee, Sang-wook, Yoon, Ho-Geun, Choi, Kyung-Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496411/
https://www.ncbi.nlm.nih.gov/pubmed/25991668