Radiosynthesis, In Vivo Biological Evaluation, and Imaging of Brain Lesions with [(123)I]-CLINME, a New SPECT Tracer for the Translocator Protein

The high affinity translocator protein (TSPO) ligand 6-chloro-2-(4′-iodophenyl)-3-(N,N-methylethyl)imidazo[1,2-a]pyridine-3-acetamide (CLINME) was radiolabelled with iodine-123 and assessed for its sensitivity for the TSPO in rodents. Moreover neuroinflammatory changes on a unilateral excitotoxic le...

Descripción completa

Detalles Bibliográficos
Autores principales: Mattner, F., Quinlivan, M., Greguric, I., Pham, T., Liu, X., Jackson, T., Berghofer, P., Fookes, C. J. R., Dikic, B., Gregoire, M.-C., Dolle, F., Katsifis, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496498/
https://www.ncbi.nlm.nih.gov/pubmed/26199457
http://dx.doi.org/10.1155/2015/729698

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496498/
https://www.ncbi.nlm.nih.gov/pubmed/26199457
http://dx.doi.org/10.1155/2015/729698

Ejemplares similares