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Early CD8 T-cell memory precursors and terminal effectors exhibit equipotent in vivo degranulation

Early after priming, effector CD8 T cells are distinguished into memory precursor and short-lived effector cell subsets (MPECs and SLECs). Here, we delineated a distinct in vivo heterogeneity in killer cell lectin-like receptor G1 (KLRG-1) expression, which was strongly associated with diverse MPEC...

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Detalles Bibliográficos
Autores principales: Yuzefpolskiy, Yevgeniy, Baumann, Florian M., Kalia, Vandana, Sarkar, Surojit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496536/
https://www.ncbi.nlm.nih.gov/pubmed/25066419
http://dx.doi.org/10.1038/cmi.2014.48