In vivo efficacy and molecular docking of designed peptide that exhibits potent antipneumococcal activity and synergises in combination with penicillin

We have previously designed a series of antimicrobial peptides (AMPs) and in the current study, the in vivo therapeutic efficacy and toxicity were investigated. Among all the peptides, DM3 conferred protection to a substantial proportion of the lethally infected mice caused by a strain of penicillin...

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Detalles Bibliográficos
Autores principales: Le, Cheng-Foh, Yusof, Mohd Yasim Mohd, Hassan, Mahmood Ameen Abdulla, Lee, Vannajan Sanghiran, Isa, Diyana Mohd, Sekaran, Shamala Devi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496672/
https://www.ncbi.nlm.nih.gov/pubmed/26156658
http://dx.doi.org/10.1038/srep11886

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496672/
https://www.ncbi.nlm.nih.gov/pubmed/26156658
http://dx.doi.org/10.1038/srep11886

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