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Seeking a Mechanism for the Toxicity of Oligomeric α-Synuclein
In a number of neurological diseases including Parkinson’s disease (PD), α‑synuclein is aberrantly folded, forming abnormal oligomers, and amyloid fibrils within nerve cells. Strong evidence exists for the toxicity of increased production and aggregation of α-synuclein in vivo. The toxicity of α-syn...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496673/ https://www.ncbi.nlm.nih.gov/pubmed/25816357 http://dx.doi.org/10.3390/biom5020282 |