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Anti-Amyloidogenic Properties of Some Phenolic Compounds

A family of 21 polyphenolic compounds consisting of those found naturally in danshen and their analogues were synthesized and subsequently screened for their anti-amyloidogenic activity against the amyloid beta peptide (Aβ(42)) of Alzheimer’s disease. After 24 h incubation with Aβ(42), five compound...

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Detalles Bibliográficos
Autores principales: Porzoor, Afsaneh, Alford, Benjamin, Hügel, Helmut M., Grando, Danilla, Caine, Joanne, Macreadie, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496683/
https://www.ncbi.nlm.nih.gov/pubmed/25898401
http://dx.doi.org/10.3390/biom5020505