Protein Degradation Pathways Regulate the Functions of Helicases in the DNA Damage Response and Maintenance of Genomic Stability

Degradation of helicases or helicase-like proteins, often mediated by ubiquitin-proteasomal pathways, plays important regulatory roles in cellular mechanisms that respond to DNA damage or replication stress. The Bloom’s syndrome helicase (BLM) provides an example of how helicase degradation pathways...

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Detalles Bibliográficos
Autores principales: Sommers, Joshua A., Suhasini, Avvaru N., Brosh, Robert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496686/
https://www.ncbi.nlm.nih.gov/pubmed/25906194
http://dx.doi.org/10.3390/biom5020590

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496686/
https://www.ncbi.nlm.nih.gov/pubmed/25906194
http://dx.doi.org/10.3390/biom5020590

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