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Base Flipping in Open Complex Formation at Bacterial Promoters

In the process of transcription initiation, the bacterial RNA polymerase binds double-stranded (ds) promoter DNA and subsequently effects strand separation of 12 to 14 base pairs (bp), including the start site of transcription, to form the so-called “open complex” (also referred to as RP(o)). This c...

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Detalles Bibliográficos
Autores principales: Karpen, Mary E., deHaseth, Pieter L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496690/
https://www.ncbi.nlm.nih.gov/pubmed/25927327
http://dx.doi.org/10.3390/biom5020668