Extracellular Adenosine Generation in the Regulation of Pro-Inflammatory Responses and Pathogen Colonization

Adenosine, an immunomodulatory biomolecule, is produced by the ecto-enzymes CD39 (nucleoside triphosphate dephosphorylase) and CD73 (ecto-5'-nucleotidase) by dephosphorylation of extracellular ATP. CD73 is expressed by many cell types during injury, infection and during steady-state conditions....

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Detalles Bibliográficos
Autores principales: Alam, M. Samiul, Costales, Matthew G., Cavanaugh, Christopher, Williams, Kristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496696/
https://www.ncbi.nlm.nih.gov/pubmed/25950510
http://dx.doi.org/10.3390/biom5020775

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496696/
https://www.ncbi.nlm.nih.gov/pubmed/25950510
http://dx.doi.org/10.3390/biom5020775

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