RNA-Binding Proteins: Splicing Factors and Disease

Pre-mRNA splicing is mediated by interactions of the Core Spliceosome and an array of accessory RNA binding proteins with cis-sequence elements. Splicing is a major regulatory component in higher eukaryotes. Disruptions in splicing are a major contributor to human disease. One in three hereditary di...

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Detalles Bibliográficos
Autores principales: Fredericks, Alger M., Cygan, Kamil J., Brown, Brian A., Fairbrother, William G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496701/
https://www.ncbi.nlm.nih.gov/pubmed/25985083
http://dx.doi.org/10.3390/biom5020893

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496701/
https://www.ncbi.nlm.nih.gov/pubmed/25985083
http://dx.doi.org/10.3390/biom5020893

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