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Initial Events in Bacterial Transcription Initiation

Transcription initiation is a highly regulated step of gene expression. Here, we discuss the series of large conformational changes set in motion by initial specific binding of bacterial RNA polymerase (RNAP) to promoter DNA and their relevance for regulation. Bending and wrapping of the upstream du...

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Detalles Bibliográficos
Autores principales: Ruff, Emily F., Record, M. Thomas, Artsimovitch, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496709/
https://www.ncbi.nlm.nih.gov/pubmed/26023916
http://dx.doi.org/10.3390/biom5021035