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Revealing Missing Human Protein Isoforms Based on Ab Initio Prediction, RNA-seq and Proteomics

Biological and biomedical research relies on comprehensive understanding of protein-coding transcripts. However, the total number of human proteins is still unknown due to the prevalence of alternative splicing. In this paper, we detected 31,566 novel transcripts with coding potential by filtering o...

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Detalles Bibliográficos
Autores principales: Hu, Zhiqiang, Scott, Hamish S., Qin, Guangrong, Zheng, Guangyong, Chu, Xixia, Xie, Lu, Adelson, David L., Oftedal, Bergithe E., Venugopal, Parvathy, Babic, Milena, Hahn, Christopher N., Zhang, Bing, Wang, Xiaojing, Li, Nan, Wei, Chaochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496727/
https://www.ncbi.nlm.nih.gov/pubmed/26156868
http://dx.doi.org/10.1038/srep10940