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Annotation of suprachromosomal families reveals uncommon types of alpha satellite organization in pericentromeric regions of hg38 human genome assembly
Centromeric alpha satellite (AS) is composed of highly identical higher-order DNA repetitive sequences, which make the standard assembly process impossible. Because of this the AS repeats were severely underrepresented in previous versions of the human genome assembly showing large centromeric gaps....
Autori principali: | , , , , , |
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Natura: | Online Articolo testo |
Lingua: | English |
Pubblicazione: |
Elsevier
2015
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Soggetti: | |
Accesso online: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496801/ https://www.ncbi.nlm.nih.gov/pubmed/26167452 http://dx.doi.org/10.1016/j.gdata.2015.05.035 |