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Annotation of suprachromosomal families reveals uncommon types of alpha satellite organization in pericentromeric regions of hg38 human genome assembly
Centromeric alpha satellite (AS) is composed of highly identical higher-order DNA repetitive sequences, which make the standard assembly process impossible. Because of this the AS repeats were severely underrepresented in previous versions of the human genome assembly showing large centromeric gaps....
Autores principales: | Shepelev, V.A., Uralsky, L.I., Alexandrov, A.A., Yurov, Y.B., Rogaev, E.I., Alexandrov, I.A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496801/ https://www.ncbi.nlm.nih.gov/pubmed/26167452 http://dx.doi.org/10.1016/j.gdata.2015.05.035 |
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