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Annotation of suprachromosomal families reveals uncommon types of alpha satellite organization in pericentromeric regions of hg38 human genome assembly

Centromeric alpha satellite (AS) is composed of highly identical higher-order DNA repetitive sequences, which make the standard assembly process impossible. Because of this the AS repeats were severely underrepresented in previous versions of the human genome assembly showing large centromeric gaps....

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Detalles Bibliográficos
Autores principales: Shepelev, V.A., Uralsky, L.I., Alexandrov, A.A., Yurov, Y.B., Rogaev, E.I., Alexandrov, I.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496801/
https://www.ncbi.nlm.nih.gov/pubmed/26167452
http://dx.doi.org/10.1016/j.gdata.2015.05.035

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