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Triptolide potentiates lung cancer cells to cisplatin-induced apoptosis by selectively inhibiting the NER activity

BACKGROUND: Cisplatin and many other platinum-based compounds are important anticancer drugs that are used in treating many cancer types. The development of cisplatin-resistant cancer cells, however, quickly diminishes the effectiveness of these drugs and causes treatment failure. New strategies tha...

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Detalles Bibliográficos
Autores principales: Wang, Gan, Wang, Xing, Xu, Xiaoxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496860/
https://www.ncbi.nlm.nih.gov/pubmed/26161259
http://dx.doi.org/10.1186/s40364-015-0043-2