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Melanoma tumor growth is accelerated in a mouse model of sickle cell disease

BACKGROUND: The effect of sickle cell disease (SCD) on tumor growth is unknown. Sickled red blood cells may form aggregates within the microvasculature of hypoxic tumors and reduce blood flow leading to impairment of tumor growth. However, there is a paucity of data related to tumor growth in SCD. M...

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Detalles Bibliográficos
Autores principales: Wang, Jintao, Tran, Jennifer, Wang, Hui, Luo, Wei, Guo, Chiao, Harro, David, Campbell, Andrew D., Eitzman, Daniel T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496890/
https://www.ncbi.nlm.nih.gov/pubmed/26161296
http://dx.doi.org/10.1186/s40164-015-0014-1