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HIV-1 and HIV-2 exhibit similar mutation frequencies and spectra in the absence of G-to-A hypermutation

BACKGROUND: Human immunodeficiency virus type 2 (HIV-2) is often distinguished clinically by lower viral loads, reduced transmissibility, and longer asymptomatic periods than for human immunodeficiency virus type 1 (HIV-1). Differences in the mutation frequencies of HIV-1 and HIV-2 have been hypothe...

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Detalles Bibliográficos
Autores principales: Rawson, Jonathan M O, Landman, Sean R, Reilly, Cavan S, Mansky, Louis M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496919/
https://www.ncbi.nlm.nih.gov/pubmed/26160407
http://dx.doi.org/10.1186/s12977-015-0180-6