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Is interleukin-1β a culprit in macrophage-adipocyte crosstalk in obesity?
Adipose tissue remodeling occurs in obesity, characterized by adipocyte hypertrophy and increased infiltration of macrophages which also shift to a proinflammatory phenotype. Factors derived from these macrophages significantly alter adipocyte function, such as repressing adipogenesis, inducing infl...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Taylor & Francis
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496963/ https://www.ncbi.nlm.nih.gov/pubmed/26167419 http://dx.doi.org/10.4161/21623945.2014.979661 |