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Transcriptome sequencing of microglial cells stimulated with TLR3 and TLR4 ligands
BACKGROUND: Resident macrophages in the CNS microglia become activated and produce proinflammatory molecules upon encountering bacteria or viruses. TLRs are a phylogenetically conserved diverse family of sensors that drive innate immune responses following interactions with PAMPs. TLR3 and TLR4 reco...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497376/ https://www.ncbi.nlm.nih.gov/pubmed/26159724 http://dx.doi.org/10.1186/s12864-015-1728-5 |