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Transcriptome sequencing of microglial cells stimulated with TLR3 and TLR4 ligands

BACKGROUND: Resident macrophages in the CNS microglia become activated and produce proinflammatory molecules upon encountering bacteria or viruses. TLRs are a phylogenetically conserved diverse family of sensors that drive innate immune responses following interactions with PAMPs. TLR3 and TLR4 reco...

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Detalles Bibliográficos
Autores principales: Das, Amitabh, Chai, Jin Choul, Kim, Sun Hwa, Lee, Young Seek, Park, Kyoung Sun, Jung, Kyoung Hwa, Chai, Young Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497376/
https://www.ncbi.nlm.nih.gov/pubmed/26159724
http://dx.doi.org/10.1186/s12864-015-1728-5