Structures of the scanning and engaged states of the mammalian SRP-ribosome complex

The universally conserved signal recognition particle (SRP) is essential for the biogenesis of most integral membrane proteins. SRP scans the nascent chains of translating ribosomes, preferentially engaging those with hydrophobic targeting signals, and delivers these ribosome-nascent chain complexes...

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Detalles Bibliográficos
Autores principales: Voorhees, Rebecca M, Hegde, Ramanujan S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497383/
https://www.ncbi.nlm.nih.gov/pubmed/26158507
http://dx.doi.org/10.7554/eLife.07975

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497383/
https://www.ncbi.nlm.nih.gov/pubmed/26158507
http://dx.doi.org/10.7554/eLife.07975

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