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Structures of the scanning and engaged states of the mammalian SRP-ribosome complex
The universally conserved signal recognition particle (SRP) is essential for the biogenesis of most integral membrane proteins. SRP scans the nascent chains of translating ribosomes, preferentially engaging those with hydrophobic targeting signals, and delivers these ribosome-nascent chain complexes...
Autores principales: | Voorhees, Rebecca M, Hegde, Ramanujan S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497383/ https://www.ncbi.nlm.nih.gov/pubmed/26158507 http://dx.doi.org/10.7554/eLife.07975 |
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